BDBM445337 (S)-3-(2-((S)-1-(1-(3-cyclopropphenyl)-1-hydro-imidazol-4-yl)ethyl)amino)pyrimidin-4-yl)-4-isopropyl-1-methylimidazolidine-2-one::US10682352, Compound 52

SMILES CC(C)[C@H]1CN(C)C(=O)N1c1ccnc(N[C@@H](C)c2cn(cn2)-c2cccc(c2)C2CC2)n1

InChI Key InChIKey=ZLGCMVJROIJAPM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 445337   

TargetIsocitrate dehydrogenase [NADP] cytoplasmic(Human)
Shanghai Haihe Pharmaceutical

US Patent
LigandPNGBDBM445337(US10682352, Compound 52 | (S)-3-(2-((S)-1-(1-(3-cy...)
Affinity DataIC50: 100nMAssay Description:Measurements were performed in a reaction volume of 15 uL using 384-well assay plates. Kinase enzyme, inhibitor, ATP and 1 uM peptide substrate were ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/15/2021
Entry Details
US Patent