BDBM445628 US10683294, Compound 1.033

SMILES CCc1cccc(CC)c1-n1nc2c(CN(C(=O)C(C)(C)C)C2(C)C)c1-c1ccc(F)c2[nH]ccc12

InChI Key InChIKey=MGULEQFOPDTTJR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 445628   

TargetC5a anaphylatoxin chemotactic receptor 1(Human)
Chemocentryx

US Patent
LigandPNGBDBM445628(US10683294, Compound 1.033)
Affinity DataIC50: 27.5nMAssay Description:cAMP treated U937 cells expressing C5aR were centrifuged and resuspended in assay buffer (20 mM HEPES pH 7.1, 140 mM NaCl, 1 mM CaCl2, 5 mM MgCl2, an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/16/2021
Entry Details
Go to US Patent