BDBM445732 US10669240, Compound 28

SMILES Fc1cc(F)cc(CNC(=O)c2n[nH]c3ccc(cc23)-c2cncc(CN3CCCCC3)c2)c1

InChI Key InChIKey=YGXACIDLZGUBTN-UHFFFAOYSA-N

Data  1 IC50  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 445732   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Samumed

US Patent

LigandBDBM445732(US10669240, Compound 28)Copy SMILESCopy InChI

Affinity DataEC50:  2nMAssay Description:SH-SY5Y cells are cultured in DMEM/F-12 medium supplemented with 15% FBS, Non-essential Amino Acid and Penicillin/Streptamycin. Two days before treat...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/21/2021
Entry Details
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TargetProto-oncogene Wnt-1(Human)
Samumed

US Patent

LigandBDBM445732(US10669240, Compound 28)Copy SMILESCopy InChI

Affinity DataIC50: 3.10E+3nMAssay Description:Reporter cell lines were generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a W...More data for this Ligand-Target Pair

Target InfoUniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/21/2021
Entry Details
Copy BDB DOIUS Patent

Copy reaction URL