BDBM445869 US10669240, Compound 1267

SMILES O=C(NCCN1CCOCC1)c1n[nH]c2ccc(cc12)-c1cccnc1

InChI Key InChIKey=BZVVVXRNQBZIHM-UHFFFAOYSA-N

Data  1 IC50  1 EC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 445869   

TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Samumed

US Patent

LigandBDBM445869(US10669240, Compound 1267)Copy SMILESCopy InChI

Affinity DataEC50:  5nMAssay Description:SH-SY5Y cells are cultured in DMEM/F-12 medium supplemented with 15% FBS, Non-essential Amino Acid and Penicillin/Streptamycin. Two days before treat...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/21/2021
Entry Details
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TargetProto-oncogene Wnt-1(Human)
Samumed

US Patent

LigandBDBM445869(US10669240, Compound 1267)Copy SMILESCopy InChI

Affinity DataIC50: 1.50E+3nMAssay Description:Reporter cell lines were generated by stably transducing cells of cancer cell lines (e.g., colon cancer) with a lentiviral construct that include a W...More data for this Ligand-Target Pair

Target InfoUniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
2/21/2021
Entry Details
Copy BDB DOIUS Patent

Copy reaction URL