BDBM446101 N-{2-[4-(4-chlorophenoxy)piperidin-1-yl]-2-[4-(difluoromethyl)- 1,3-thiazol-5-yl]ethyl}quinoline-5-carboxamide::US10669267, Compound 35

SMILES FC(F)c1ncsc1C(CNC(=O)c1cccc2ncccc12)N1CCC(CC1)Oc1ccc(Cl)cc1

InChI Key InChIKey=LDSRRNIBPGQGHF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 446101   

TargetP2X purinoceptor 7(Rat)
Axxam

US Patent
LigandPNGBDBM446101(N-{2-[4-(4-chlorophenoxy)piperidin-1-yl]-2-[4-(dif...)
Affinity DataIC50: 323nMAssay Description:Ca2+ influx was measured in HEK-293 cells stably transfected with the receptor using Screen Quest Fluo-8 No Wash Calcium Assay Kit (AAt Bioquest ). B...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/21/2021
Entry Details
Go to US Patent