BDBM4464 4-(5-Chloro-2-hydroxyphenylamino)-6,7-dimethoxyquinoline-3-carbonitrile Hydrochloride::4-[(5-chloro-2-hydroxyphenyl)amino]-6,7-dimethoxyquinoline-3-carbonitrile::6,7-dialkoxyquinoline-3-carbonitrile deriv. 27

SMILES COc1cc2ncc(C#N)c(Nc3cc(Cl)ccc3O)c2cc1OC

InChI Key InChIKey=IVWBIVZBYRCUFO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 4464   

TargetEpidermal growth factor receptor(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM4464(4-[(5-chloro-2-hydroxyphenyl)amino]-6,7-dimethoxyq...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition autophosphorylation of EGFR in human DiFi cells after 2 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Korea Institute of Science and Technology

Curated by ChEMBL
LigandPNGBDBM4464(4-[(5-chloro-2-hydroxyphenyl)amino]-6,7-dimethoxyq...)
Affinity DataIC50: 1.70E+4nMAssay Description:The EGF-R kinase autophosphorylation activity was measured by DELFIA/time-resolved fluorometry with excitation at 340 nm and emission at 615 nm. Po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2005
Entry Details Article
PubMed