BDBM446750 4-[6-(3- hydroxy- propylamino) imidazo[1,2- b]pyridazin- 3-yl]- 2-methoxy- phenol::US10688093, Compound 229_0248_0314::US10688093, Compound BF000146250 (229_0248_0314)::US11701353, Compound 229_0248_0314

SMILES COc1cc(ccc1O)-c1cnc2ccc(NCCCO)nn12

InChI Key InChIKey=KGDVXQORBWBIHS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 446750   

TargetTyrosine-protein kinase Fyn(Human)
Pathways Neuro Pharma

US Patent
LigandPNGBDBM446750(US10688093, Compound BF000146250 (229_0248_0314) |...)
Affinity DataIC50: 206nMAssay Description:The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetTyrosine-protein kinase Fyn(Human)
Pathways Neuro Pharma

US Patent
LigandPNGBDBM446750(US10688093, Compound BF000146250 (229_0248_0314) |...)
Affinity DataIC50: 329nMAssay Description:The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent