BDBM44681 5-(ethylamino)-2-(1-naphthalenyl)-4-oxazolecarbonitrile::5-(ethylamino)-2-(1-naphthyl)-1,3-oxazole-4-carbonitrile::5-(ethylamino)-2-(1-naphthyl)oxazole-4-carbonitrile::5-(ethylamino)-2-naphthalen-1-yl-1,3-oxazole-4-carbonitrile::MLS000065147::SMR000078645::cid_974197

SMILES CCNc1oc(nc1C#N)-c1cccc2ccccc12

InChI Key InChIKey=IGZOETULBZWTBX-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 44681   

LigandPNGBDBM44681(MLS000065147 | 5-(ethylamino)-2-(1-naphthalenyl)-4...)
Affinity DataEC50:  3.68E+3nMAssay Description:Southern Research Molecular Libraries Screening Center (SRMLSC) Southern Research Institute (Birmingham, Alabama) NIH Molecular Libraries Screening C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2011
Entry Details
PCBioAssay
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Harvard Medical School

Curated by ChEMBL
LigandPNGBDBM44681(MLS000065147 | 5-(ethylamino)-2-(1-naphthalenyl)-4...)
Affinity DataIC50: 120nMAssay Description:Inhibition of recombinant N-terminal His6-tagged human reticulocyte 12/15-lipoxygenase using arachidonic acid as substrate by UV-vis spectrometric an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed