BDBM447061 4-[6-(3,4- dimethoxyphenyl) imidazo[1,2- b]pyridazin-3- yl]-2-methoxy- phenol::US10688093, Compound 828_0314_0079::US10688093, Compound BF000726453 (828_0314_0079)::US11701353, Compound 828_0314_0079

SMILES COc1ccc(cc1OC)-c1ccc2ncc(-c3ccc(O)c(OC)c3)n2n1

InChI Key InChIKey=HLWIUMWUZXNFTC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 447061   

TargetTyrosine-protein kinase Fyn(Human)
Pathways Neuro Pharma

US Patent
LigandPNGBDBM447061(4-[6-(3,4- dimethoxyphenyl) imidazo[1,2- b]pyridaz...)
Affinity DataIC50: 39.4nMAssay Description:The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent

TargetTyrosine-protein kinase Fyn(Human)
Pathways Neuro Pharma

US Patent
LigandPNGBDBM447061(4-[6-(3,4- dimethoxyphenyl) imidazo[1,2- b]pyridaz...)
Affinity DataIC50: 44.5nMAssay Description:The assay procedure determines the IC50 of each potential FYN kinase inhibitor by measuring the enzyme catalyzed ATP-dependent phosphorylation of the...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2021
Entry Details
US Patent