BDBM448545 N-(2-(4-((5-methyl-1,3,4-oxadiazol-2-yl)methyl)piperazin-1- yl)-5-(trifluoromethyl)phenyl)-5-(pyridin-4-yl)furan-2- carboxamide::US10696661, Compound 6

SMILES Cc1nnc(CN2CCN(CC2)c2ccc(cc2NC(=O)c2ccc(o2)-c2ccncc2)C(F)(F)F)o1

InChI Key InChIKey=CVLHNFCYNXWQLD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 448545   

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandPNGBDBM448545(N-(2-(4-((5-methyl-1,3,4-oxadiazol-2-yl)methyl)pip...)
Affinity DataIC50: 88.3nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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