BDBM448548 5-methyl-N-(2-(4-((furan-2-yl)methyl)piperazin-1-yl)-5- (trifluoromethyl)phenyl)furan-2-carboxamide::US10696661, Compound 8

SMILES Cc1ccc(o1)C(=O)Nc1cc(ccc1N1CCN(Cc2ccco2)CC1)C(F)(F)F

InChI Key InChIKey=XRHFXIQYYDGMMC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 448548   

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandPNGBDBM448548(5-methyl-N-(2-(4-((furan-2-yl)methyl)piperazin-1-y...)
Affinity DataIC50: 17.6nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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