BDBM448647 N-(2-(4-((1H-pyrazol-3-yl)methyl)piperazin-1-yl)-5- (trifluoromethyl)-phenyl)-5-(tetrahydro-2H-pyran-4-yl)furan- 2-carboxamide::US10696661, Compound 14

SMILES FC(F)(F)c1ccc(N2CCN(Cc3cc[nH]n3)CC2)c(NC(=O)c2ccc(o2)C2CCOCC2)c1

InChI Key InChIKey=MVEIOMZCQWWFHS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 448647   

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandPNGBDBM448647(N-(2-(4-((1H-pyrazol-3-yl)methyl)piperazin-1-yl)-5...)
Affinity DataIC50: 3.5nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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