BDBM448672 N-(2-(4-((1-methyl-1H-pyrazol-3-yl)methyl)piperazin-1-yl)-5- (trifluoromethyl)phenyl)-5-(pyridin-4-yl)furan-2-carboxamide::US10696661, Compound 25

SMILES Cn1ccc(CN2CCN(CC2)c2ccc(cc2NC(=O)c2ccc(o2)-c2ccncc2)C(F)(F)F)n1

InChI Key InChIKey=KLMOANGVWGFFMF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 448672   

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandPNGBDBM448672(N-(2-(4-((1-methyl-1H-pyrazol-3-yl)methyl)piperazi...)
Affinity DataIC50: 11.3nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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