BDBM448693 N-(2-(4-(1H-imidazol-4-ylmethyl)piperazin-1-yl)-5- (trifluoromethyl)phenyl)-picolinamide::US10696661, Compound 41::US10696661, Compound 73

SMILES FC(F)(F)c1ccc(N2CCN(Cc3c[nH]cn3)CC2)c(NC(=O)c2ccccn2)c1

InChI Key InChIKey=PJYVAAVMWJCOKH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 448693   

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandPNGBDBM448693(US10696661, Compound 73 | N-(2-(4-(1H-imidazol-4-y...)
Affinity DataIC50: 28.7nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandPNGBDBM448693(US10696661, Compound 73 | N-(2-(4-(1H-imidazol-4-y...)
Affinity DataIC50: 28.7nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
Go to US Patent