BDBM448698 5-methyl-N-(2-(4-((5-methylfuran-2-yl)methyl)piperazin-1-yl)- 5-(trifluoromethyl)phenyl)furan-2-carboxamide::US10696661, Compound 46

SMILES Cc1ccc(CN2CCN(CC2)c2ccc(cc2NC(=O)c2ccc(C)o2)C(F)(F)F)o1

InChI Key InChIKey=CASNLCVMRIKYAS-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 448698   

TargetSRSF protein kinase 1(Human)
Exonate

US Patent
LigandPNGBDBM448698(5-methyl-N-(2-(4-((5-methylfuran-2-yl)methyl)piper...)
Affinity DataIC50: 10.7nMAssay Description:Screening of a series of molecules identified compounds (Compounds 5, 8, 16 to 18 and 43 of Table 3) that had improved potency against SRPK1 against ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/2/2021
Entry Details
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