BDBM449862 US10703741, Compound I-5

SMILES CN(C)C\C=C\C(=O)N[C@H]1CNC[C@@H]1NC(=O)c1ccc2n(C)c(nc2c1)-c1cc2cccnc2n1CC1CC1

InChI Key InChIKey=ZLBVSEGRTNQHQH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 449862   

TargetProtein-arginine deiminase type-4(Mouse)
Padlock Therapeutics

US Patent
LigandPNGBDBM449862(US10703741, Compound I-5)
Affinity DataIC50: 550nMAssay Description:Compounds were solubilized in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent

TargetProtein-arginine deiminase type-4(Human)
Padlock Therapeutics

US Patent
LigandPNGBDBM449862(US10703741, Compound I-5)
Affinity DataIC50: 5.50E+3nMAssay Description:Compounds were solubilized in 100% DMSO to achieve 100 mM final compound concentration. Compound stock solutions were stored at RT. A series of dilut...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/8/2021
Entry Details
US Patent