BDBM450376 1-{2,6-dichloro-4-[(2S)-1,1,1-trifluoro-2-hydroxy-2-propanyl]phenyl}-3-{[3-(trifluoromethyl)-1,2,4-oxadiazole-5-yl]methyl}urea::US10676438, Example 26

SMILES C[C@](O)(c1cc(Cl)c(NC(=O)NCc2nc(no2)C(F)(F)F)c(Cl)c1)C(F)(F)F

InChI Key InChIKey=OBVGGWLMWWAMTD-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 450376   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Ono Pharmaceutical

US Patent
LigandPNGBDBM450376(US10676438, Example 26 | 1-{2,6-dichloro-4-[(2S)-1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Using HEK293 cell overexpressing a human ether-a-go-go-related gene (hERG), the maximum tale current of the hERG IKr current induced by redepolarizat...More data for this Ligand-Target Pair
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Date in BDB:
3/10/2021
Entry Details
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