BDBM450615 (2S,3R)-3-((S or R)-2-(1- (2,5-bis(trifluoromethyl)- benzyl)piperidin-4-yl)-1- methyl-1,2,3,4- tetrahydroquinolin-7-yl)- 3-cyclopropyl-2-methyl propanoic acid::US10676458, Example 9

SMILES C[C@@H]([C@@H](C1CC1)c1ccc2CCC(C3CCN(Cc4cc(ccc4C(F)(F)F)C(F)(F)F)CC3)N(C)c2c1)C(O)=O

InChI Key InChIKey=ZKPMTGOFQKOTDI-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 450615   

TargetFree fatty acid receptor 1(Human)
Merch Sharp & Dohne Corp. Rahway

US Patent
LigandPNGBDBM450615(US10676458, Example 9 | (2S,3R)-3-((S or R)-2-(1- ...)
Affinity DataEC50:  289nMAssay Description:The assay was performed in 384-well format. HEK cells stably expressing human GPR40 were plated at 7500 cells per well in growth medium (DMEM/10% fet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
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