BDBM450622 Sodium (2S,3R)-3-cyclopropyl-3-((R or S)-3-(2′-fluoro-5′-methoxy-[1,1′-biphenyl]-4-yl)-4-methyl-3,4-dihydro-2H benzo-[b][1,4]oxazin-6-yl)-2-methyl propanoate; and Sodium (2S,3R)-3-cyclopropyl-3-((S or R)-3-(2′-fluoro-5′-methoxy-[1,1′-biphenyl]-4-yl)-4-methyl-3,4-dihydro-2H-benzo[b][1,4]oxazin-6-yl)-2-methyl propanoate::US10676458, Example 20::US10676458, Example 21

SMILES COc1ccc(F)c(c1)-c1ccc(cc1)C1COc2ccc(cc2N1C)[C@@H]([C@H](C)C([O-])=O)C1CC1

InChI Key InChIKey=XJFUDULFEFPDON-UHFFFAOYSA-M

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 450622   

TargetFree fatty acid receptor 1(Human)
Merch Sharp & Dohne Corp. Rahway

US Patent
LigandPNGBDBM450622(US10676458, Example 20 | Sodium (2S,3R)-3-cyclopro...)
Affinity DataEC50:  0.800nMAssay Description:The assay was performed in 384-well format. HEK cells stably expressing human GPR40 were plated at 7500 cells per well in growth medium (DMEM/10% fet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent

TargetFree fatty acid receptor 1(Human)
Merch Sharp & Dohne Corp. Rahway

US Patent
LigandPNGBDBM450622(US10676458, Example 20 | Sodium (2S,3R)-3-cyclopro...)
Affinity DataEC50:  12nMAssay Description:The assay was performed in 384-well format. HEK cells stably expressing human GPR40 were plated at 7500 cells per well in growth medium (DMEM/10% fet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent