BDBM450809 US10676469, Compound 24::US11124504, Cpd. No. 24

SMILES CCc1cc2cc(-c3nc(C)no3)c(nc2cc1F)N1CCC(CC1)N[C@H]1CCOC1

InChI Key InChIKey=MJKPQNFBJXGWDM-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 450809   

TargetKappa-type opioid receptor(Human)
Blackthorn Therapeutics

US Patent
LigandPNGBDBM450809(US10676469, Compound 24 | US11124504, Cpd. No. 24)
Affinity DataIC50: 5.5nMAssay Description:The cell line for the OPRK1 antagonist assay stably expresses the following elements: The carboxy terminus of the OPRK1 receptor has a 7-amino acid l...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent

TargetMu-type opioid receptor(Human)
Blackthorn Therapeutics

US Patent
LigandPNGBDBM450809(US10676469, Compound 24 | US11124504, Cpd. No. 24)
Affinity DataIC50: 1.00E+3nMAssay Description:The purpose of this assay is to confirm the potency and selectivity of compounds synthesized to be OPRK1 Antagonists. This assay monitors the OPRMu1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent