BDBM450976 US10676470, Compound 14

SMILES NCCCCC(NC(=O)[C@@H]1CCCN(C1)C(=O)CCc1ccccc1)C(=O)c1nc2ccccc2s1

InChI Key InChIKey=LZIQKKGKSQRLJR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 450976   

TargetLys-gingipain W83(Porphyromonas gingivalis)
Cortexyme

US Patent
LigandPNGBDBM450976(US10676470, Compound 14)
Affinity DataIC50: 5.5nMAssay Description:The capacities of compounds of the present invention to inhibit the activity of lysine gingipain were measured in a fluorogenic assay similar to thos...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/11/2021
Entry Details
Go to US Patent