BDBM451370 US10709718, Compound 7

SMILES CC(C)(CO)COP(O)(=O)c1ccc(NC(=O)Nc2ccccc2)cc1

InChI Key InChIKey=LFSZNGOOVJKHSO-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 451370   

TargetDiacylglycerol O-acyltransferase 1(Human)
Metabasis Therapeutics

US Patent
LigandPNGBDBM451370(US10709718, Compound 7)
Affinity DataIC50: 550nMAssay Description:The inhibition of DGAT-1 activity can be assessed in intestinal microsome preparations by monitoring the incorporation of radiolabeled fatty acyl-CoA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
US Patent