BDBM452538 6-((3-((3R,5R)-5-(4- chlorophenyl)tetra- hydrofuran-3-yl)-1,2,4- oxadiazol-5-yl)methyl)- 1-methyl-1,6-dihydro- 7H-[1,2,3]triazolo[4,5- d]pyrimidin-7-one::US10710994, Example 16

SMILES Cn1nnc2ncn(Cc3nc(no3)[C@@H]3CO[C@H](C3)c3ccc(Cl)cc3)c(=O)c12

InChI Key InChIKey=VAUMAOIZDODPOE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452538   

LigandPNGBDBM452538(6-((3-((3R,5R)-5-(4- chlorophenyl)tetra- hydrofura...)
Affinity DataIC50: 4.90nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
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Date in BDB:
3/14/2021
Entry Details
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LigandPNGBDBM452538(6-((3-((3R,5R)-5-(4- chlorophenyl)tetra- hydrofura...)
Affinity DataIC50: 2.70nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
Go to US Patent