BDBM452584 2-amino-3-((3-((3R,5R)- 5-(4-chlorophenyl) tetrahydrofuran-3-yl)- 1,2,4-oxadiazol-5- yl)methyl)pyrido[2,3-d] pyrimidin-4(3H)-one::US10710994, Example 62

SMILES Nc1nc2ncccc2c(=O)n1Cc1nc(no1)[C@@H]1CO[C@H](C1)c1ccc(Cl)cc1

InChI Key InChIKey=QSDHOQUBCGWXAS-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452584   

LigandPNGBDBM452584(2-amino-3-((3-((3R,5R)- 5-(4-chlorophenyl) tetrahy...)
Affinity DataIC50: 8.29nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
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LigandPNGBDBM452584(2-amino-3-((3-((3R,5R)- 5-(4-chlorophenyl) tetrahy...)
Affinity DataIC50: 2.70nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
Go to US Patent