BDBM452604 2-((3-((3R,5R)-5-(4- chlorophenyl)tetrahydro- furan-3-yl)-1,2,4-oxadiazol- 5-yl)methyl)-2H-pyrido [1,2-d][1,2,4]triazine-1,6- dione::US10710994, Example 82

SMILES Clc1ccc(cc1)[C@H]1C[C@@H](CO1)c1noc(Cn2ncn3c(cccc3=O)c2=O)n1

InChI Key InChIKey=ADSGDRJGOSICMK-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 452604   

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Genentech

US Patent

LigandBDBM452604(2-((3-((3R,5R)-5-(4- chlorophenyl)tetrahydro- fura...)Copy SMILESCopy InChI

Affinity DataIC50: 2.40nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/14/2021
Entry Details
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