BDBM452609 2-amino-6-((3-((3R,5R)- 5-(4-chlorophenyl)tetra- hydrofuran-3-yl)-1,2,4- oxadiazol-5-yl)methyl) pyrido[2,3-d]pyridazin- 5(6H)-one::US10710994, Example 87

SMILES Nc1ccc2c(cnn(Cc3nc(no3)[C@@H]3CO[C@H](C3)c3ccc(Cl)cc3)c2=O)n1

InChI Key InChIKey=OMCPTRKQFMHMFO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452609   

LigandPNGBDBM452609(2-amino-6-((3-((3R,5R)- 5-(4-chlorophenyl)tetra- h...)
Affinity DataIC50: 10.5nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
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LigandPNGBDBM452609(2-amino-6-((3-((3R,5R)- 5-(4-chlorophenyl)tetra- h...)
Affinity DataIC50: 3.5nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
Go to US Patent