BDBM452634 1-((3-((3R,5R)-5-(4- chlorophenyl)tetrahydro- furan-3-yl)-1,2,4- oxadiazol-5-yl)methyl)- 1H-imidazo[4,5-b] pyrazin-2-amine::US10710994, Example 112

SMILES Nc1nc2nccnc2n1Cc1nc(no1)[C@@H]1CO[C@H](C1)c1ccc(Cl)cc1

InChI Key InChIKey=OOABNTZYAYDDFY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452634   

LigandPNGBDBM452634(1-((3-((3R,5R)-5-(4- chlorophenyl)tetrahydro- fura...)
Affinity DataIC50: 10.8nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
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LigandPNGBDBM452634(1-((3-((3R,5R)-5-(4- chlorophenyl)tetrahydro- fura...)
Affinity DataIC50: 3.80nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
Go to US Patent