BDBM452647 2-amino-1-((3-((3R,5R)- 5-(3-fluorophenyl) tetrahydrofuran-3-yl)- 1,2,4-oxadiazol-5-yl) methyl)-7-methyl-1,7- dihydro-6H-purin-6-one::US10710994, Example 125

SMILES Cn1cnc2nc(N)n(Cc3nc(no3)[C@@H]3CO[C@H](C3)c3cccc(F)c3)c(=O)c12

InChI Key InChIKey=AZZRAZUXGHJAOV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452647   

LigandPNGBDBM452647(2-amino-1-((3-((3R,5R)- 5-(3-fluorophenyl) tetrahy...)
Affinity DataIC50: 40.5nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
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Date in BDB:
3/14/2021
Entry Details
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LigandPNGBDBM452647(2-amino-1-((3-((3R,5R)- 5-(3-fluorophenyl) tetrahy...)
Affinity DataIC50: 3.10nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
Go to US Patent