BDBM452778 1-((3-((1R,5S,6r)-3- (2,3-difluorophenyl)- 3-azabicyclo[3.1.0] hexan-6-yl)-1,2,4- oxadiazol-5-yl) methyl)-7-methyl- 1,7-dihydro-6H-::US10711004, Example 100

SMILES Cn1cnc2ncn(Cc3nc(no3)[C@@H]3[C@H]4CN(C[C@@H]34)c3cccc(F)c3F)c(=O)c12

InChI Key InChIKey=UCDSHIQKQTZWPG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452778   

LigandPNGBDBM452778(1-((3-((1R,5S,6r)-3- (2,3-difluorophenyl)- 3-azabi...)
Affinity DataIC50: 12.8nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
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LigandPNGBDBM452778(1-((3-((1R,5S,6r)-3- (2,3-difluorophenyl)- 3-azabi...)
Affinity DataIC50: 2.5nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
Go to US Patent