BDBM452803 1-((3-((1S,5S,6R)-3- (4-fluorophenyl) bicyclo[3.1.0]hex-2- en-6-yl)-1,2,4-oxa- diazol-5-yl)methyl)- 7-methyl-1,7- dihydro-6H-purin-6-one::US10711004, Example 125

SMILES Cn1cnc2ncn(Cc3nc(no3)[C@@H]3[C@H]4CC(=C[C@@H]34)c3ccc(F)cc3)c(=O)c12

InChI Key InChIKey=DHGRAFMYKRWRSJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452803   

LigandPNGBDBM452803(1-((3-((1S,5S,6R)-3- (4-fluorophenyl) bicyclo[3.1....)
Affinity DataIC50: 7.48nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
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LigandPNGBDBM452803(1-((3-((1S,5S,6R)-3- (4-fluorophenyl) bicyclo[3.1....)
Affinity DataIC50: 3nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
Go to US Patent