BDBM452816 3-((3-((1R,5S,6r)-3- (4-chloropyridin-2-yl)- 3-azabicyclo[3.1.0] hexan-6-yl)-1,2,4- oxadiazol-5-yl) methyl)-5-methyl- pyrazolo[5,1-f][1,2,4]::US10711004, Example 138

SMILES Cc1cnn2ncn(Cc3nc(no3)[C@@H]3[C@H]4CN(C[C@@H]34)c3cc(Cl)ccn3)c(=O)c12

InChI Key InChIKey=XQGUQUOCTSQNDD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452816   

LigandPNGBDBM452816(3-((3-((1R,5S,6r)-3- (4-chloropyridin-2-yl)- 3-aza...)
Affinity DataIC50: 15.1nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
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LigandPNGBDBM452816(3-((3-((1R,5S,6r)-3- (4-chloropyridin-2-yl)- 3-aza...)
Affinity DataIC50: 5.5nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
Go to US Patent