BDBM452851 3-((3-((1R,5S,6r)-3- (3-chlorophenyl)-3- azabicyclo[3.1.0] hexan-6-yl)-1,2,4- oxadiazol-5-yl)methyl)- 5-methyl-3,5- dihydropyrido[3,2-d] pyrimidine-4,6-dione::US10711004, Example 173

SMILES Cn1c2c(ccc1=O)ncn(Cc1nc(no1)[C@@H]1[C@H]3CN(C[C@@H]13)c1cccc(Cl)c1)c2=O

InChI Key InChIKey=XSFCKBIGLBUTHE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 452851   

LigandPNGBDBM452851(3-((3-((1R,5S,6r)-3- (3-chlorophenyl)-3- azabicycl...)
Affinity DataIC50: 3.97nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
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Date in BDB:
3/14/2021
Entry Details
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