BDBM452892 6-((3-((1R,5S,6r)-3- (3-chlorophenyl)-3- azabicyclo[3.1.0] hexan-6-yl)-1,2,4- oxadiazol-5-yl) methyl)pyrido[2,3-d] pyridazin-5(6H)-one::US10711004, Example 214

SMILES Clc1cccc(c1)N1C[C@H]2[C@@H](C1)[C@@H]2c1noc(Cn2ncc3ncccc3c2=O)n1

InChI Key InChIKey=SMIMKERZYSZTRX-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 452892   

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Genentech

US Patent

LigandBDBM452892(6-((3-((1R,5S,6r)-3- (3-chlorophenyl)-3- azabicycl...)Copy SMILESCopy InChI

Affinity DataIC50: 2.88nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
3/14/2021
Entry Details
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