BDBM452933 8-amino-7-methyl-1- [[3-[(1S,5S,6R)-3- phenyl-6-bicyclo [3.1.0]hex-2-enyl]- 1,2,4-oxadiazol-5-yl] methyl]purin-6-one::US10711004, Example 255

SMILES Cn1c(N)nc2ncn(Cc3nc(no3)[C@@H]3[C@H]4CC(=C[C@@H]34)c3ccccc3)c(=O)c12

InChI Key InChIKey=AHJAJTHWNBFJBF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452933   

LigandPNGBDBM452933(8-amino-7-methyl-1- [[3-[(1S,5S,6R)-3- phenyl-6-bi...)
Affinity DataIC50: 33.3nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
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LigandPNGBDBM452933(8-amino-7-methyl-1- [[3-[(1S,5S,6R)-3- phenyl-6-bi...)
Affinity DataIC50: 3.80nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
Go to US Patent