BDBM452934 4-[(1S,5S,6R)-6-[5- [(7-methyl-6-oxo- purin-1-yl)methyl]- 1,2,4-oxadiazol-3- yl]-3-bicyclo[3.1.0] hex-2-enyl]benzonitrile::US10711004, Example 256

SMILES Cn1cnc2ncn(Cc3nc(no3)[C@@H]3[C@H]4CC(=C[C@@H]34)c3ccc(cc3)C#N)c(=O)c12

InChI Key InChIKey=CQGSBWGNKKNJCP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452934   

LigandPNGBDBM452934(4-[(1S,5S,6R)-6-[5- [(7-methyl-6-oxo- purin-1-yl)m...)
Affinity DataIC50: 21.7nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
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LigandPNGBDBM452934(4-[(1S,5S,6R)-6-[5- [(7-methyl-6-oxo- purin-1-yl)m...)
Affinity DataIC50: 6.60nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
Go to US Patent