BDBM452941 8-chloro-7-methyl-1- [[3-[(1R,5R,6S)-3- phenyl-6-bicyclo [3.1.0]hex-2-enyl]- 1,2,4-oxadiazol-5-yl] methyl]purin-6-one::US10711004, Example 263

SMILES Cn1c(Cl)nc2ncn(Cc3nc(no3)[C@H]3[C@@H]4CC(=C[C@H]34)c3ccccc3)c(=O)c12

InChI Key InChIKey=LGMMPJBTYVKDBK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452941   

LigandPNGBDBM452941(8-chloro-7-methyl-1- [[3-[(1R,5R,6S)-3- phenyl-6-b...)
Affinity DataIC50: 15.8nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
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LigandPNGBDBM452941(8-chloro-7-methyl-1- [[3-[(1R,5R,6S)-3- phenyl-6-b...)
Affinity DataIC50: 6.5nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
Go to US Patent