BDBM452953 2-[[3-[(1R,5R,6S)-3- phenyl-6-bicyclo [3.1.0]hex-2-enyl]- 1,2,4-oxadiazol-5-yl] methyl]pyrido[1,2-a] pyrazine-1,6-dione::US10711004, Example 275

SMILES O=c1cccc2n1ccn(Cc1nc(no1)[C@H]1[C@@H]3CC(=C[C@H]13)c1ccccc1)c2=O

InChI Key InChIKey=IORSMGCJYPRZSZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452953   

LigandPNGBDBM452953(2-[[3-[(1R,5R,6S)-3- phenyl-6-bicyclo [3.1.0]hex-2...)
Affinity DataIC50: 11.9nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
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Date in BDB:
3/14/2021
Entry Details
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LigandPNGBDBM452953(2-[[3-[(1R,5R,6S)-3- phenyl-6-bicyclo [3.1.0]hex-2...)
Affinity DataIC50: 6.5nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
Go to US Patent