BDBM452957 6-[[3-[(1R,5S)-3- (1,3-benzothiazol-6- yl)-3-azabicyclo [3.1.0]hexan-6-yl]- 1,2,4-oxadiazol-5-yl] methyl]pyrido[2,3-d] pyridazin-5-one::US10711004, Example 279

SMILES O=c1n(Cc2nc(no2)[C@@H]2[C@H]3CN(C[C@@H]23)c2ccc3ncsc3c2)ncc2ncccc12

InChI Key InChIKey=PIERVTPSZKKBMN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 452957   

LigandPNGBDBM452957(6-[[3-[(1R,5S)-3- (1,3-benzothiazol-6- yl)-3-azabi...)
Affinity DataIC50: 11.2nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
Go to US Patent

LigandPNGBDBM452957(6-[[3-[(1R,5S)-3- (1,3-benzothiazol-6- yl)-3-azabi...)
Affinity DataIC50: 5.60nMAssay Description:The IC50 (effective concentration) of compounds on the human TRPA1 channel was determined using a FLIPR Tetra instrument. CHO cells expressing TRPA1 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2021
Entry Details
Go to US Patent