BDBM453711 2-(9-Ethyl-8-fluoro-6-methyl-9H-carbazol-3-yl)-4-fluoro-1-(2-methoxyethyl)-1H-benzimidazole-5-carboxylic Acid::US10730856, Example 8

SMILES CCn1c2ccc(cc2c2cc(C)cc(F)c12)-c1nc2c(F)c(ccc2n1CCOC)C(O)=O

InChI Key InChIKey=YZYHHSOYSLSBOV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 453711   

TargetProstaglandin E2 receptor EP4 subtype(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM453711(2-(9-Ethyl-8-fluoro-6-methyl-9H-carbazol-3-yl)-4-f...)
Affinity DataIC50: 1.90nMAssay Description:5. 1 Detection PrincipleBinding of prostaglandin D2 to the human PGD receptor induces activation of membrane-bound adenylate cyclases and leads to th...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent