BDBM453987 US10730863, Example 434

SMILES OC(=O)c1cc(cc2nc(sc12)C12CCC(CC1)(CC2)OCc1c(onc1-c1c(Cl)cncc1Cl)C1CC1)C(F)(F)F

InChI Key InChIKey=XKJVRZKELVRCDG-UHFFFAOYSA-N

Data  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 453987   

TargetBile acid receptor(Human)
Bristol-Myers Squibb

US Patent
LigandPNGBDBM453987(US10730863, Example 434)
Affinity DataEC50:  18nMAssay Description:A Gal4-hFXR fusion construct reporter system was used as the primary assay to characterize compound activity. A construct including 5 copies of the G...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent