BDBM454165 BDBM50246195::US10716791, Code KP-289

SMILES CC(C)NC(=O)[C@H](CCN1CCN(C)CC1)NC(=O)c1ccco1

InChI Key InChIKey=IAMFZBVVYSMZDZ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 454165   

TargetProtein-arginine deiminase type-4(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM454165(BDBM50246195 | US10716791, Code KP-289)
Affinity DataKi:  4.88E+5nMAssay Description:Inhibition of full length human GST-tagged PAD4 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2019
Entry Details Article
PubMed
TargetProtein-arginine deiminase type-4(Human)
University of Toronto

Curated by ChEMBL
LigandPNGBDBM454165(BDBM50246195 | US10716791, Code KP-289)
Affinity DataKi:  4.88E+5nMAssay Description:Materials: PAD1, PAD2, PAD3 and PAD4 were purchased from commercial sources. Assay buffer: 50 mM Tris pH 7.5, 100 mM NaCl, 10 mM CaCl2, 5 mM DTT. Col...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetProtein-arginine deiminase type-2(Mouse)
University Health Network

US Patent
LigandPNGBDBM454165(BDBM50246195 | US10716791, Code KP-289)
Affinity DataKi:  1.79E+6nMAssay Description:Materials: PAD1, PAD2, PAD3 and PAD4 were purchased from commercial sources. Assay buffer: 50 mM Tris pH 7.5, 100 mM NaCl, 10 mM CaCl2, 5 mM DTT. Col...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
US Patent

TargetProtein-arginine deiminase type-2(Mouse)
University Health Network

US Patent
LigandPNGBDBM454165(BDBM50246195 | US10716791, Code KP-289)
Affinity DataKi:  1.84E+6nMAssay Description:Inhibition of full length mouse GST-tagged PAD2 expressed in baculovirus infected Sf9 insect cells preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/29/2019
Entry Details Article
PubMed