BDBM454577 US10717746, Example 57

SMILES CC1(C)Cc2ncc(-c3cc(NC(=O)[C@H]4CCC[C@H](C4)NC(=O)C4COC4)ncc3Cl)n2C1

InChI Key InChIKey=ONDUAKFQKLPDKJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 454577   

TargetCyclin-dependent kinase 9(Human)
Astrazeneca

US Patent
LigandPNGBDBM454577(US10717746, Example 57)
Affinity DataIC50: 3nMAssay Description:Activity of CDK9 was determined in-vitro using a mobility shift assay on a Caliper LC3000 reader (Caliper/PerkinElmer), which measures fluorescence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent

TargetCyclin-dependent kinase 9(Human)
Astrazeneca

US Patent
LigandPNGBDBM454577(US10717746, Example 57)
Affinity DataIC50: 4nMAssay Description:Activity of CDK9 was determined in-vitro using a mobility shift assay on a Caliper LC3000 reader (Caliper/PerkinElmer), which measures fluorescence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2021
Entry Details
Go to US Patent