BDBM4551 4-Phenylamino-3-quinolinecarbonitrile deriv. 28::4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-7-{[5-(4-morpholinyl)pentyl]oxy}-3-quinolinecarbonitrile::4-[(2,4-dichloro-5-methoxyphenyl)amino]-6-methoxy-7-{[5-(morpholin-4-yl)pentyl]oxy}quinoline-3-carbonitrile

SMILES COc1cc(Nc2c(cnc3cc(OCCCCCN4CCOCC4)c(OC)cc23)C#N)c(Cl)cc1Cl

InChI Key InChIKey=IHWCITLWMVRUQP-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 4551   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Wyeth-Ayerst Research

LigandPNGBDBM4551(4-[(2,4-Dichloro-5-methoxyphenyl)amino]-6-methoxy-...)
Affinity DataIC50: 2.5nMAssay Description:Src kinase activity was measured in an ELISA format. IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the tra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/16/2005
Entry Details Article
PubMed