BDBM455875 2-(3-(cyclopropylethynyl)-5- (2-methoxypyrimidin-5-yl)- 2H-indazol-2-yl)-N-hydroxy- 3-phenylpropanamide::US10723705, No. I-0031

SMILES COc1ncc(cn1)-c1ccc2nn(C(Cc3ccccc3)C(=O)NO)c(C#CC3CC3)c2c1

InChI Key InChIKey=FBSBNKLZIXNLBN-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 455875   

TargetHistone deacetylase 8(Human)
Incyte

US Patent
LigandPNGBDBM455875(2-(3-(cyclopropylethynyl)-5- (2-methoxypyrimidin-5...)
Affinity DataIC50: 50nMAssay Description:HDAC-Glo I/II Assay Kit was purchased from Promega Corporation (Madison, Wis.), including the following components: HDAC-Glo I/II Buffer (25 mM Tris ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/28/2021
Entry Details
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