BDBM456544 US10723742, Example 273::US10723742, Example 277::US11510915, Example 277

SMILES CC(C)(O)Cn1nnc2cc(c(F)c(Br)c12)-c1ccc(cc1-c1ccc(C#N)c(F)c1)C(=O)N1[C@@H]2CC[C@H]1[C@@H](N)C2

InChI Key InChIKey=BALNFYBTXFLMEH-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 456544   

TargetLysine-specific histone demethylase 1A(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM456544(US10723742, Example 277 | US10723742, Example 273 ...)
Affinity DataIC50: 0.190nMAssay Description:The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2021
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM456544(US10723742, Example 277 | US10723742, Example 273 ...)
Affinity DataIC50: 0.420nMAssay Description:The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/30/2021
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM456544(US10723742, Example 277 | US10723742, Example 273 ...)
Affinity DataIC50: 0.190nMAssay Description:The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
Go to US Patent

TargetLysine-specific histone demethylase 1A(Human)
Taiho Pharmaceutical

US Patent
LigandPNGBDBM456544(US10723742, Example 277 | US10723742, Example 273 ...)
Affinity DataIC50: 0.420nMAssay Description:The conditions for measuring inhibitory activity of compounds against LSD1 activity were determined with reference to a document available from the w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/28/2023
Entry Details
Go to US Patent