BDBM458379 US10752631, Compound 10

SMILES COc1cc(OC)cc(c1)C#Cc1nc(C2CCN(C2)C(=O)\C=C\CN(C)C)n2ccnc(N)c12

InChI Key InChIKey=CGEQLJAOZFZKHW-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 458379   

TargetFibroblast growth factor receptor 2(Human)
Guangzhou Innocare Pharma Tech

US Patent
LigandPNGBDBM458379(US10752631, Compound 10)
Affinity DataIC50: 50nMAssay Description:The in vitro activity of FGFR2 was determined by assaying the phosphorylation level of the substrate in the kinase reaction, by means of an HTRF kina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Guangzhou Innocare Pharma Tech

US Patent
LigandPNGBDBM458379(US10752631, Compound 10)
Affinity DataIC50: 50nMAssay Description:The in vitro activity of FGFR3 was determined by assaying the phosphorylation level of the substrate in the kinase reaction, by means of an HTRF kina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
US Patent