BDBM458381 US10752631, Compound 12

SMILES COc1cc(OC)cc(c1)C#Cc1nc(C2CN(C2)C#CC)n2ccnc(N)c12

InChI Key InChIKey=NDFPXCRYULSGKF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 458381   

TargetFibroblast growth factor receptor 2(Human)
Guangzhou Innocare Pharma Tech

US Patent
LigandPNGBDBM458381(US10752631, Compound 12)
Affinity DataIC50: 275nMAssay Description:The in vitro activity of FGFR2 was determined by assaying the phosphorylation level of the substrate in the kinase reaction, by means of an HTRF kina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
US Patent

TargetFibroblast growth factor receptor 3(Human)
Guangzhou Innocare Pharma Tech

US Patent
LigandPNGBDBM458381(US10752631, Compound 12)
Affinity DataIC50: 275nMAssay Description:The in vitro activity of FGFR3 was determined by assaying the phosphorylation level of the substrate in the kinase reaction, by means of an HTRF kina...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
US Patent