BDBM458499 2-(2-Fluoro-6-methoxyphenyl)-N-(1-methyl-4-(methyl)tetrahydro-2H-pyran-4-yl)amino)-1H-indazol-5-yl)pyrimidine-4-carboxamide::US10745388, Example 7

SMILES COc1cccc(F)c1-c1nccc(n1)C(=O)Nc1ccc2n(C)ncc2c1N(C)C1CCOCC1

InChI Key InChIKey=PIYUCMIUJIBJCT-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 458499   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Incyte

US Patent

LigandBDBM458499(2-(2-Fluoro-6-methoxyphenyl)-N-(1-methyl-4-(methyl...)Copy SMILESCopy InChI

Affinity DataKi: <100nMAssay Description:A stock solution of 1 mM test compound was prepared in DMSO. The compound plate was prepared by 3-fold and 11-point serial dilutions. 0.1 μL of ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/13/2021
Entry Details
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