BDBM458504 (S) N-(4-((1-acetylpyrrolidin-3-yl)(methyl)amino)-1-methyl-1H-indazol-5-yl)-2-(2-fluoro-6-methoxyphenyl)pyrimidine-4-carboxamide::US10745388, Example 12

SMILES COc1cccc(F)c1-c1nccc(n1)C(=O)Nc1ccc2n(C)ncc2c1N(C)[C@H]1CCN(C1)C(C)=O

InChI Key InChIKey=GYORGPZJJBCWOR-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 458504   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Incyte

US Patent

LigandBDBM458504((S) N-(4-((1-acetylpyrrolidin-3-yl)(methyl)amino)-...)Copy SMILESCopy InChI

Affinity DataKi: <100nMAssay Description:A stock solution of 1 mM test compound was prepared in DMSO. The compound plate was prepared by 3-fold and 11-point serial dilutions. 0.1 μL of ...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
4/13/2021
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL