BDBM458754 US10759766, Compound C016

SMILES Fc1cccc(NC(=O)Nc2cccc(c2)C(=O)c2ccc3ncc(nc3c2)N2CCOCC2)c1

InChI Key InChIKey=RHZRFLBGCJFPMY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 458754   

TargetVascular endothelial growth factor receptor 2(Human)
Neupharma

US Patent
LigandPNGBDBM458754(US10759766, Compound C016)
Affinity DataIC50: 100nMAssay Description:KDR (VEGFR2): Inhibitory activities of compounds against KDR (VEGFR2) were also measured by Invitrogen using Z′-LYTE Method as described above ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent

TargetSerine/threonine-protein kinase B-raf [V600E](Human)
Neupharma

US Patent
LigandPNGBDBM458754(US10759766, Compound C016)
Affinity DataIC50: 100nMAssay Description:BRAF and BRAF V600E: Inhibitory activities Inhibitory activities of compounds against BRAF, and BRAF V600E were measured by Invitrogen using Z′...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
US Patent